Development of a safer laboratory vervet monkey model for the study of human African trypanosomiasis
نویسندگان
چکیده
منابع مشابه
Development of a safer laboratory vervet monkey model for the study of human African trypanosomiasis
BACKGROUND There are three subspecies of Trypanosoma brucei: T. b. gambiense, T. b. rhodesiense and T. b. brucei. The first two are infectious to humans, whilst T. b. brucei is not. Identifying an animal model of T. b. brucei that mimics human African trypanosomiasis (HAT) would enable researchers to study HAT without subjecting themselves to undue risks such as accidental infection. OBJECTIV...
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There are no oral drugs for human African trypanosomiasis (HAT, sleeping sickness). A successful oral drug would have the potential to reduce or eliminate the need for patient hospitalization, thus reducing healthcare costs of HAT. The development of oral medications is a key objective of the Consortium for Parasitic Drug Development (CPDD). In this study, we investigated the safety, pharmacoki...
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ژورنال
عنوان ژورنال: African Journal of Laboratory Medicine
سال: 2014
ISSN: 2225-2010,2225-2002
DOI: 10.4102/ajlm.v3i1.100